Learn about SPM’s and Chronic Pain

Dr. Kristina Fruechtl Blog

SPM stands for Specialized Pro-resolving Mediator.  So what does it mean to you?  Less pain and a more active lifestyle…


SPM’a are extracted from fish oil and concentrated into supplement form. They are different than traditional fish oil or EPA/DHA  and other long-chain polyunsaturated fatty acid supplements and are not a substitute for them.  EPA and DHA may be converted into SPM’s, however there are many steps in this process and the ability for the body to go through those steps depends upon a person’s health status. SPM’s aid in the resolution of the immune response without suppressing immune defenses.  The immune response is a normal and healthy response to physical stressors.  When the body gets stuck in a prolonged immune response which can turn to be chronic, this causes ongoing pain and stress on the body.  SPM’s help the body resolve inflammation (acute or chronic) and therefore resolve pain.  This is different than suppressing inflammation with an anti-inflammatory, whether the anti-inflammatory is a natural remedy or a medication. Appropriate SPM production by the body relies on one’s lifestyle and current health status and behaviors. Insufficient production may interfere with the resolution of an immune response, therefore prolonging inflammation and pain.

It is no longer believed that the resolution of the immune inflammatory process is a passive process and that is amazing.

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Thanks and good health to you!


Information for this post was obtained from Metagenics supplement company in support of their OmegaGenics SPM Active product.